ADPKD is a leading cause
of kidney failure that is easily diagnosed and treatable.
ADPKD (Polycystic Kidney Disease) affects more than 1 in every 1000 births and is the 4th leading cause of kidney failure (ESRD). About 50% of patients with this genetic abnormality will develop ESRD by the time they turn 60. Because the symptoms don't show up until one's 30s or 40s, it often goes undiagnosed for decades. Diagnosis is simple and usually involves an ultrasound, and if needed, a blood test. Though effective treatment is available to prevent painful symptoms, and delay or prevent kidney failure, the condition remains underdiagnosed and undertreated.
In ADPKD the kidneys can grow abnormally large, reaching up to 30 pounds each in weight, causing abdominal pain, blood in the urine, and kidney stones. Tolvaptan has been shown to slow down the increase in kidney size, and to preserve kidney function (TEMPO & REPRISE trials). It's most effective if started early; however, most people don't develop symptoms until middle age and don't seek treatment until later. If diagnosed early, you may be able to start treatment and avoid the painful & debilitating complications, and delay or avoid kidney failure.
If you have been diagnosed with ADPKD and need an experienced specialist to guide you through treatment options, or if you suspect you might have ADPKD and would like to be tested, call me to arrange a free phone consultation.